To mark the release of the new episode, BBC Radio 5 Live will bring listeners a ‘day of hope’ across their shows with stories from cancer patients, and family members, live broadcasts from Great Ormond Street Hospital and The Institute of Cancer Research, as well as conversations with medical experts.

Of the episode, host and creator of Girl Vs Cancer Lauren Mahon said: “It’s the first time we’ll be recording in front of a live audience – something we’ve wanted to do for the longest time. It’ll be bittersweet that Deb isn’t with us to fulfil our dream but we hope we do both her and Rach proud. It’s our chance to properly honour our amazing podcast and celebrate the legacy of our amazing pals.”

You, Me and the Big C will be available on BBC Sounds from Monday 30 January.

You, Me and the Big C: a special new episode of the award-winning BBC podcast to be released