The actress won the Best Actress in a Leading Role for Still Alice, a film about a woman who has to come to terms with being diagnosed with early onset Alzheimer's disease.

On the red carpet, she proudly told reporters 'Karl made this for me'. Her stylist, Leslie Fremar told Style.com that she had been friends with the designer for many years.

Julianne was up against four other actresses; Reese Witherspoon for Wild, Felicity Jones for The Theory of Everything, Rosamund Pike for Gone Girl, and Marion Cotillard for Two Days, One Night.

This isn't the first time the 54-year-old was nominated for an Oscar; she has been up for an Academy Award four times before. Her first time was for Best Actress in a Supporting Role in Boogie Nights and her second time was for Best Actress in a Leading Role for The End of the Affair.

Her third and fourth times were at the 2003 Oscars for two different films; one award for Best Actress in a Supporting Role for The Hours, and the other was for Best Actress in a Leading Role for Far From Heaven.

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Julianne Moore arrives at the Oscars 2015